
【基本情况】
姚佳,研究员,甘肃省生物治疗与再生医学重点实验室,学术型博士研究生导师(临床药物治疗),学术型硕士研究生导师(临床检验诊断学)。
【学习经历】
2000.9—2005.07 兰州大学基础医学院临床医学,学士
2006.9—2011.07 兰州大学生命科学学院分子生物学,博士(硕博连读)士
【工作经历】
2011.07— 2017.11 兰州大学第一医院,助理研究员
2017.12— 2024.11 兰州大学第一医院,副研究员
2024.12 至今 兰州大学第一医院,研究员
【目前承担课程】
《临床科学研究与管理》、《研究生SCI论文写作》。
【主要科研成果】
研究方向:
1.干细胞相关的组织器官再生技术
2.基于临床数据的靶向药物筛选鉴定及新药研发工作
主持或参与科研项目:
- 甘肃省科技重大专项-科技成果转化引导专项,以代谢重编程关键因子IDH3B为靶点的抗肿瘤药物开发,2025/01至2027/12,100万元,在研,主持;
- 国家自然科学基金,靶向促黏多肽R-peptide对iPSCs来源肝脏类器官培养体系的优化及机制研究,2022/01至2025/12,36万元,在研,主持;
- 兰州市城关区科技计划项目,靶向促黏多肽对干细胞来源肝脏类器官培养体系的优化及机制研究,2022/12至2025/12,30万元。
在研,主持;发表主要论文或专著:
- Zongbin Sun, Qiuxia Zheng, Yue Zhang, Chongyang Bai, Fanghong Wang, Ping Yang, Dan Zhu, Xiaoyuan Liu, Shang Li, Desheng Liu, Rui Li, Liu He, Jia Yao,* and Xun Li* Hydrogel Loaded with Aminoethyl Anisamide Modified Exosomes Attenuates Hepatic Fibrosis by Targeting Activated Hepatic Stellate CellsHydrogel Loaded with Aminoethyl Anisamide Modified Exosomes Attenuates Hepatic Fibrosis by Targeting Activated Hepatic Stellate Cells, ACS nano,2025, doi.org/10.1021/acsnano.5c06003
- Wenkang Fu, Yanyan Lin, Mingzhen Bai, Jia Yao*, Jinqiu Yuan*, Wenhua Zhang h*, Wenbo Meng*, Beyond ribosomal function: RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing, Acta Pharmaceutica Sinica B, 2024,14(9):3931e3948
- Yongcui Mao, Pinyan Liu, Jiayun Wei, Ye Xie, Qiuxia Zheng, Rui Li, Jia Yao*, Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway. Journal of Translational Internal Medicine, (2024),10:12(5) 478-494
- Xuekai Hu, Yue Zhang, Yanchen Li, Qiuxia Zheng, Haixia Zhao, Yun Zhang, Jingman Ni*, Jia Yao*, Application and mechanism of anticancer peptides in organoid models of intrahepatic cholangiocarcinoma, Scientific Reports, (2025) 15:22870
- Pinyan Liu, Jiayun Wei, Ye Xie, Qiuxia Zheng, Rui Li, Jia Yao*, Cell Therapy for Androgenetic Alopecia: Elixir or Trick? Stem Cell Reviews and Reports, (2023) 05 June
- Pinyan Liu, Yongcui Mao, Ye Xie and Jiayun Wei, Jia Yao*, Stem Cells for Treatment of Liver Fibrosis/Cirrhosis: Clinical Progress and Therapeutic Potential,Stem Cell Research & Therapy, (2022) 13:356
- Jia Yao, Man Yang, Lawrence Atteh, Pinyan Liu, Yongcui Mao, Wenbo Meng* and Xun Li; A pancreas tumor derived organoid study: from drug screen to precision medicine, Cancer Cell International, (2021) 21:398.
- Jia Yao, Yue Yu, Scott L. Nyberg*; Induced Pluripotent Stem Cells for the Treatment of Liver Diseases: Novel Concepts, Cells Tissues Organs, 2020,7:1-17.
【联系方式】
E-mail:yaoj06@lzu.edu.cn
甘公网安备 62010202000472号